New Triterpenic Glucoside from Beesia calthaefolia (Maxim.) Ulbr. Native to China  

中国特有药用植物铁破锣中的新皂甙类成分(英文)

作　　者：鞠建华[1] 刘东[1] 林耕[1] 许旭东[1] 杨峻山[1] 涂光忠[2] 马立斌[2] 

机构地区：[1]中国协和医科大学中国医学科学院药用植物研究所,北京100094 [2]北京微量化学研究所,北京100060

出　　处：《Acta Botanica Sinica》2001年第9期983-987,共5页Acta Botanica Sinica（植物学报：英文版）

基　　金：SupportedbytheNationalNaturalScienceFoundationofChina ( 2 9732 0 40 )

摘　　要：Five compounds (1 - 5) were isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr. Based on chemical and spectral evidence, their structures were determined as beesic acid (9-phenyl-2E, 4E, 6E, 8E-nontetraenoic acid, 1), vanillic acid (2), oleanolic acid-3-O-alpha.-L-arabinopyranosyl-28-O-alpha -L-rhanmopyranosyl-(1 --> 4)-beta -D-glucopyranosyl-(1 --> 6)-beta -D-glucopyranosyl ester (3), hederasaponin B (oleanolic acid-3-O-alpha -L-rhanmopyranosyl-(1-->2)-alpha -L-arabinopyranosyl-28-O-alpha -L-rhamnopyranosyl-(1-->4)beta -D-glucopyranosyl-(1-->6)-beta -D-glucopyranosyl ester, 4) and beesioside Q (oleanolic acid-3-O-beta -D-glucopyranosyl-(1-->3)-alpha -L-rhamnopyranosyl-(1-->2)-alpha -L-arabinopyranosyl-28-O-alpha -L-rhamnopyranosyl-(1--> 4)-beta -D-glucopyranosyl-(1-->6)-beta -D-glucopyranosyl ester, 5), respectively. Compound 1 was isolated from natural sources for the first time and compound 5 was a new compound.从铁破锣 (Beesiacalthaefolia (Maxim .)Ulbr.)根茎中分离得到 5个化合物 (1～ 5 ) ,经化学和波谱学方法鉴定 ,其中 2个为有机酸———铁破锣酸 (beesicacid ,9_phenyl_2E ,4E ,6E ,8E_nontetraenoicacid ,1)和香草酸 (2 ) ;3个为齐墩果酸型三萜皂甙 :oleanolicacid_3_O_α_L_arabinopyranosyl_2 8_O_α_L_rhamnopyranosyl_(1→ 4)_β_D_glucopyranosyl_(1→ 6 )_β_D_glucopyranosylester (3) ,hederasaponinB (oleanolicacid_3_O_α_L_rhamnopyranosyl_(1→ 2 )_α_L_arabinopyranosyl_2 8_O_α_L_rhamnopyranosyl_(1→ 4)_β_D_glucopyranosyl_(1→ 6 )_β_D_glucopyranosylester,4)和铁破锣皂甙Q (beesiosideQ ,oleanolicacid_3_O_β_D_glucopyranosyl_(1→ 3)_α_L_rhamnopyranosyl_(1→ 2 )_α_L_arabinopyranosyl_2 8_O_α_L_rhamnopyranosyl_(1→ 4)_β_D_glucopyranosyl_(1→ 6 )_β_D_glucopyranosylester,5 )。化合物 1系首次从自然界中分离得到 ,化合物 5为新化合物。

关 键 词：RANUNCULACEAE Beesia calthaefolia oleanane-type glycoside beesic acid beesioside Q 

分 类 号：R284[医药卫生—中药学] Q946.83[医药卫生—中医学]