甘草酸铋钾对大鼠实验性胃溃疡的作用  

Effect of bismuth potassium glycyrrhizate on gastric ulcers in rat

作　　者：曹苹[1] 汪岱迪[2] 

机构地区：[1]深圳市药品检验所,广东深圳518029 [2]江苏省药品检验所,江苏南京210008

出　　处：《中草药》2001年第7期623-625,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的　研究甘草酸铋钾对胃溃疡的影响。方法　用醋酸性胃溃疡、应急性胃溃疡及幽门结扎性胃溃疡模型测定甘草酸铋钾对溃疡面积、胃液量、胃液酸度和胃蛋白酶的影响。结果　甘草酸铋钾能使溃疡面积和胃液量减小、降低胃液酸度和胃蛋白酶活性。结论　甘草酸铋钾能有效地治疗胃溃疡。Object To study the effect of bismuth potassium glycyrrhizate on gastric ulcers in rat. Methods Area of ulcer, gastric juice volume, acidity and pepsin output were measured on experimental gastric ulcer induced by acetic acid, stress and pyloric ligation in rats. Results Bismuth potassium glycyrrhizate was shown to be able to reduce areas of ulcers, gastric juice volume, acidity and pepsin output. Conclusion Bismuth potassium glycyrrhizate had antiulcer effect in rats.

关 键 词：甘草酸 甘草酸铋钾 胃溃疡 大鼠 

分 类 号：R259.731[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]