糖尿病与睡眠呼吸紊乱的关系  

Relationship between diabetes and sleep related breathing disorders

作　　者：李宏增[1] 游国雄[1] 竺士秀[1] 

机构地区：[1]第四军医大学唐都医院神经内科,陕西西安710038

出　　处：《第四军医大学学报》2001年第16期1515-1517,共3页Journal of the Fourth Military Medical University

摘　　要：目的　探讨糖尿病患者的睡眠呼吸紊乱 (sleep relat-ed breathing disorders,SRBD)特点及临床意义 .方法　非胰岛素依赖性糖尿病 (non- insulin dependentdiabetes,NIDDM)2 3例 ,睡眠呼吸暂停综合征 (sleep apnea syndrome,SAS) 13例 ,PSG结果进行对比研究 .结果　 48%的糖尿病 (DM)患者合并 SRBD;DM合并 SRBD者并发高血压及心脑血管病明显增多 17% vs73% ,P<0 .0 1;DM的 SRBD中中枢性呼吸紊乱 (CBD)占 44 .3% ,可能为 DM患者的 PSG特征 .结论　DM易发生 SRBD;SAS可能加重糖尿病 ,系因缺氧产生胰岛素抵抗以及儿茶酚胺分泌增高等所致 ;CBD可能为 PSG诊断DM的一个辅助特征 ;DM行 PSG检查 ,可早期发现加重病情的 SRBD。AIM To study the relationship between sleep related breathing disorders (SRBD) and diabetes mellitus. METHODS Twenty three non insulin dependent diabetes mellitus (NIDDM) patients were analyzed and compared with obstructive sleep apnea syndrome (OSAS) patients by polysomnography (PSG) method. RESULTS Of the DM patients 48% were accompanied with SRBD; complication of hypertension and cardio cerebral vascular diseases increased markedly (17% vs 73% P <0.01) in this group; 44% of theDM SRBD belonged to the central breathing disorder (CBD). CONCLUSION DM is likely to be complicated, and aggravated by SRBD, because hypoxemia can lead insulin resistance and the increase of catecholamine secretion. CBD may be one of the characteristics PSG in DM. PSG examination in DM patients can explore SRBD early and be helpful to DM treatment.

关 键 词：糖尿病 睡眠呼吸暂停综合征 多道睡眠描记术 

分 类 号：R587.1[医药卫生—内分泌]