早期梅毒规范驱梅治疗后梅毒螺旋体IgM抗体的变化  

Change of Serum IgM Antibodies to Treponema pallidum(Tp-IgM) of Treated Early Syphilis

作　　者：施辛[1] 石怡珍[1] 杨辰[1] 刘秀丽[1] 苏玉华[1] 

机构地区：[1]苏州大学附属第二医院皮肤科,苏州215004

出　　处：《苏州医学院学报》2001年第4期442-443,共2页Acta Academiae Medicinae Suzhou

摘　　要：目的　动态观察早期梅毒治疗后血清梅毒螺旋体IgM抗体 (Tp -IgM )的变化。 方法　采用抗体捕捉酶免疫测定技术 (Tp -IgM -Cap -ELISA) ,对 41例早期梅毒患者于治疗后每 3个月进行Tp -IgM检测 ,连续 2年。结果　治疗 6个月和 12个月后 ,分别有 2 9例、39例Tp -IgM转阴 ,转阴率为 47.5 %、97.5 %。 结论　早期梅毒规范治疗后 1年左右 ,Tp -IgM可转阴。Objective To investigate the change of serum IgM antibldy to Treponema pallidum(Tp-IgM) of treated early syphilis patients. Methods During the period of 2 years, the serum of 41 pateents with early syphilis were measured with ETI-SYPHILIS IgM EIA KIT based on antibldy capture technology every 3 months since their treament. Results By the ends of 6 and 12 months, seroconversion of Tp-IgM occurred in 29 and 39 patients with early syphilis. and the rate of seroconversion of Tp-IgM were 47.5% and 97.5% respectively. For patients with early syphilis,seroconversion of Tp-IgM occurr within about 1 year or so. Conclusion For treated early syphilis,and the rate of seroconversion of Tp-IgM occurred within about 1 year or so. This maybe helpful for following up for eary syphilis patients.

关 键 词：早期梅毒 Tp-IgM 转阴 规范驱梅治疗 梅毒螺旋体 IgM抗体变化 

分 类 号：R759.11[医药卫生—皮肤病学与性病学]