直接经皮腔内冠状动脉成形术对急性心肌梗死QT离散度的影响  

Effects of percutaneous transluminal coronary angioplasty on QT interval dispersion in acute myocardial infarcton

作　　者：江隆福[1] 陈玉峰[1] 陈国方[1] 冯海明[1] 

机构地区：[1]宁波市第二医院心内科,浙江宁波315010

出　　处：《临床心血管病杂志》2001年第9期393-394,共2页Journal of Clinical Cardiology

摘　　要：目的 :研究急性心肌梗死 (AMI)后直接经皮腔内冠状动脉成形术 (PTCA)对 QT离散度 (QTd)的影响。方法 :回顾 95例 AMI患者 ,通过测量入院时及入院后不同时间心电图。对比分析其中 6 8例 PTCA再通患者 (PTCA组 )与 2 7例未行 PTCA或溶栓患者 (对照组 )不同时间 QTd的变化。结果 :PTCA组再通即刻 QTd、Q Tcd较再通前明显延长 (P <0 .0 1) ,2 h后恢复到入院时水平 ,4h后较入院时明显缩短 (P <0 .0 1) ,以后 2 4h内相对稳定。对照组入院后 2 4h内 QTd、QTcd变化不大 (P >0 .0 5 )。结论 :AMI后成功的 PTCA治疗可以缩短心室复极的 QTd,但再灌注即刻可延长Objective: To study the effects o f percutaneous transluminal coronary angioplasty (PTCA) on QT interval dispersi on (QTd) in acute myocardial infarction (AMI). Method: Ninety-five patients with AMI were divided into P TCA group (n=68) and no-PTCA group or control group (n=27). QTd and cor rected QTd (QTcd) were measured at the admission and in different time after adm ission. Result: In PTCA group, QTd and QTcd were significantly pro longed from ( 63.7± 14.9) and ( 69.3± 17.4) msec before reperfusio n to ( 88.5± 24.3) and ( 92.1± 26.8) msec after instant reperfusio n respectively (P< 0.01). Two hours after angioplasty, they returned to the level while patients were admitted into hospital and shortened significantly (P< 0.01) 4 hours after angioplasty, and were kept stable in the subsequ ent 24 hours. On the other hand, in control group, QTd and QTcd showed no signif icant changes (P> 0.05) within 24 hour after patients were admitted into the hospital.Conclusion:Effective treatment with PTCA can shorten QTd i n patients with AMI, but QTd can be prolonged at the instant of reperfusion.

关 键 词：血管成形术 经腔冠状动脉 经皮冠状动脉 心肌梗死 QT离散度 

分 类 号：R542.22[医药卫生—心血管疾病] R540.41[医药卫生—内科学]