肠道传播的非甲非乙型肝炎病人粪便排病毒规律的检测  

A STUDY ON THE PERIOD OF VIRUS EXCRETION IN THE STOOLS OF PATIENTS OF ENTERICALLY TRANSMITTED NON-A NON-B HEPATITIS

作　　者：曹学义[1] 孙士英 刘占娥 马学众[1] 热西达[1] 王俭[1] 金喜梅[1] 董红军[1] 刘玉璋[1] 柴萍 刘崇柏[2] 庄辉[3] 王光明[4] 

机构地区：[1]新疆维吾尔自治区卫生防疫站 [2]中国预防医学科学院病毒学研究所 [3]北京医科大学 [4]中国医学科学院实验动物研究所

出　　处：《病毒学报》1989年第2期188-190,共3页Chinese Journal of Virology

摘　　要：1986年9月～1987年6月,新疆和田发生了一次非甲非乙型肝炎(HNANB)的流行,以病原学排除法判明,为肠道传播的非甲非乙型肝炎病毒所致。为了制订本病的隔离期限和控制对策提供科学依据,并为了研究其流行病学、临床学和病原学特点,我们用免疫电镜检测了6名自然感染的HNANB病人在潜伏期和急性期的60份系列粪便标本,以了解其排毒规律。现将结果报告如下。A total of 60 stool samples collected from 6 patients suffering from acute enterically transmitted non-A, non-B hepatitis were examined by immune electron microscopy ( IEM ) during an epidemic of the disease in Hetian area,Xinjiang in 1986-1987. The virus was found in feces in 5 patients, and 28.3 per cent ( 17/60 ) of the samples collected. All 3 stool samples collected 1-4 days before illness were positive for the virus. The rate of virus excretion gradually declined from 1-9 days after the onset. 14.3 per cent ( 1/7 ) of the stool samples excreted virus within 10-12 days after the onset, whereas virus was not detected in 22 samples collected 13-24 days after the onset.In 94.1 per cent of samples, the virus were obtained during late incubation period and early acute phases when SGPT was under 100IU/L. In view of thesd findings we suggest that the isolation period for this disease should be at least 2-3 weeks from the onset of the disease.

关 键 词：丙型肝炎 病毒 排泄 肠道 传播 

分 类 号：R512.630.1[医药卫生—内科学]