小剂量米非司酮对卵巢功能和子宫内膜的影响  

Effects of Low Dose Mifepristone on Ovarian Function and Endome trial Development

作　　者：林穗青[1] 李红[1] 程利南 孙巧英[1] 刘斯青[1] 

机构地区：[1]复旦大学附属中山医院妇产科,上海200032 [2]上海市计划生育技术指导所,上海200030

出　　处：《中国临床医学》2001年第3期264-265,共2页Chinese Journal of Clinical Medicine

摘　　要：目的 :了解每天口服小剂量米非司酮对卵巢功能及子宫内膜的影响。方法 :4 0名有正常月经周期的健康妇女 ,随机分成 2组 ,2 0名每天口服 2mg米非司酮 ;另 2 0名每天口服 5mg米非司酮 ,共口服 12 0d。结果 :服药期间 87.5 %妇女闭经 ,95 %妇女停止排卵 ,子宫内膜处于持续增生期。结论 :连续口服小剂量米非司酮可以抑制卵泡发育、排卵 。Objective: To study the effects of low dose mifepristone on ovary fu nction and endometrial development. Methods: Forty women with normal menstrual cycles were divided two groups.Twenty women took 2mg mifepristone daily, the others took 5mg mifepristone daily , total 120 days. Results: In the treatment period 87.5% women had gotten amenorrhea, 95% women did not ovu late. Endometrium was in proliferative phase continually. Conclusion: Daily of low dose mifepristone can restrain follicle growth, inhibite ovulation and depre ss endometrial development.

关 键 词：米非司酮 卵巢功能 子宫内膜 小剂量 避孕 

分 类 号：R984[医药卫生—药品] R169.41[医药卫生—药学]