海洛因成瘾者胰腺的透射电镜观察  

Research on Pancreas for Heroin-addicts by Transmission Electron Microscope (TEM )

作　　者：朱华[1] 李利华[1] 赵永和[1] 姚宏[1] 李跃明 

机构地区：[1]昆明医学院法医学系,昆明650031 [2]大理州公安局技术大队,大理671300

出　　处：《昆明医学院学报》2001年第3期1-3,共3页Journal of Kunming Medical College

基　　金：国家自然科学基金资助 ( 3 9760 0 76)

摘　　要：对 4例海洛因成瘾死亡者胰腺的超微病理改变进行了研究 .研究发现 ,胰腺腺泡上皮细胞线粒体不同程度肿胀、嵴断裂 ,粗面内质网丰富、扩张、分泌颗粒减少 ,可见多量聚集成堆的酶原颗粒 ;胰岛细胞粗面内质网丰富 ,线粒体丰富 ,神经内分泌颗粒丰富 ,小部分细胞神经内分泌颗粒减少 .说明海洛因对胰腺超微结构影响显著 .Research on heroin-addicts′ pancreas in 4 cases by TEM showed that mitochondria epithelial cells in pancreatic acinus swell to varying degrees with hypertrophic and dilated rough surfaced endoplasmic reticulum,and decreased secretory granules resulting in a great number of visible zymogen granules in heaps; and that rough surfaced endoplasmic reticulum in pancreatic islet cells were many and had dilated with hyperplasia mitochondrion,rich neuroendocrine granules and a small part of reduced ones. The results reveal that heroin brings about remarkable injury in ultrastructural pathology of pancreata

关 键 词：海洛因成瘾 胰腺 超微结构 透射电镜 

分 类 号：R595.5[医药卫生—内科学] R322.491[医药卫生—临床医学]