Dipasic对结核菌耐药性的研究  

Susceptibility Test of Tubercle Bacilli to Dipasic

作　　者：许学受[1] 许申[2] 管守英[1] 

机构地区：[1]安徽医科大学附属医院,230022 [2]安徽省肺科医院

出　　处：《临床肺科杂志》2001年第2期1-2,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的　了解 Dipasic对耐药菌株是否有效及其药物抑菌浓度。方法　药敏培养基内加入 10种不同浓度抗结核药物 ,加入结核菌菌液 10 - 3毫克　结果　四周后观察三种抗结核药物耐药情况　结论　 DPC是一种独立的抗结核药物对耐药结核菌都有效 ,但在 1μg浓度时仍有 3 0 %生长 ,认为用药量应加倍。Objective To know the susceptibility of Mycobacterium tuberculosis to Dipasic. Methods To add antituberculotics in 10 different Dncentrations to susceptiblity culture medium,then 10 -3 mg of tubercle bacilli were added into this culture medium.Results The susceptibility of tubercle bacilli to 3 antituberculotics were observed after 4 weeks.Conclusions DPC, an independent antituberculotics,is active to drug resistant tubercle bacilli,although there are 30% tubercle bacilli still growth in 1μg/ml.The results suggest that the dosage of DPC must be doubled.

关 键 词：Dipasic 耐药性 结核菌 抗结核药物 

分 类 号：R52[医药卫生—内科学]