黄芪总皂甙水解为黄芪甲苷的工艺研究  

Researches on Preparation Process of Astragaloside Ⅳ by All of Astragalosides

作　　者：张宇[1] 胡春玲[1] 高阳[1] 吕哲 李鑫昶 

机构地区：[1]佳木斯大学化学与药学院 [2]齐齐哈尔富拉尔基电厂医院 [3]黑龙江省海伦县医院

出　　处：《黑龙江医药科学》2001年第4期136-137,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的 :本实验寻找黄芪总皂甙水解为黄芪甲苷的有效方法。方法 :以黄芪甲苷为标准品 ,采用薄层层析技术跟踪水解产物 ,运用正交设计方法择选水解的最佳工艺。结果 :温度控制在 10 0℃ ,水解 7h的条件效果最好。结论 :本实验研究的水解方法是提高黄芪甲苷收率的有效方法 。Objective: To study the preparation process of Astragaloside Ⅳ by All of Astragalosides. Methods: The Optimal process conditions for prepareing Astragaloside Ⅳ were selected by orthogonal tests. The product, Astragaloside Ⅳprepared was followed-up by TLC. Results: The best process conditions were the temperature of 100℃and the time of 7 hours. Conclusions: Our preparation process of Astragaloside Ⅳ by All of Astragalosides is effective,worthy of popularization.

关 键 词：黄芪甲苷 制备工艺 薄层层析 

分 类 号：TQ461[化学工程—制药化工] R283[医药卫生—中药学]