复合人工滑液的正交设计  

Compound Artificial Synovia in Orthogonal Test

作　　者：虞路清[1] 李久青[2] 顾正秋[2] 张蓓[2] 

机构地区：[1]北京科技大学应用科学学院,北京100083 [2]北京科技大学材料科学与工程学院,北京100083

出　　处：《北京科技大学学报》2001年第5期435-438,484,共5页Journal of University of Science and Technology Beijing

基　　金：国家自然科学基金资助课题(No.990413651)

摘　　要：利用正交实验设计配制由透明质酸ＨＡ、Ｌα－ＤＰＰＣ磷脂和ｙ－球蛋白３种成分构成的复合人工滑液，在ＰＶＡ－Ｈ／ＰＶＡ－Ｈ，ＰＶＡ－Ｈ／３１６Ｌ Ｓ Ｓ两类人工关节摩擦副上，利用自制振子式摩擦仪测定其摩擦学参数，初步确定出复合人工滑液中３种成分的适宜配比．The compound artificial synovia was prepared according to the table of orthogonal test design, which three factors-Hyaluronic Acid, γ- globulin and Lα-DPPC and five levels were considered. A pendulum type friction test made by author was used to determine the friction coefficient of two kinds of tribology slide pairs-PVA-H/PVA-H and PVA-H/316L S S lubricated by the compound artificial synovia, the appropriate properties of three factors in the compound artificial synovia selected were ascertained finally.

关 键 词：透明质酸 复合人工滑液 正交实验设计 人工关节润滑剂 

分 类 号：R318.17[医药卫生—生物医学工程] TH117.22[医药卫生—基础医学]