兔脑内血肿模型的制作  

Establishment of rabbit model of intracerebral hematoma

作　　者：陶胜忠[1] 苏芳忠[1] 杨金庆 张鹏远[1] 宋乐[1] 

机构地区：[1]河南医科大学第二附属医院神经外科,郑州450003 [2]中原油田总医院神经外科,濮阳457001

出　　处：《河南医科大学学报》2001年第6期674-675,共2页Journal of Henan Medical University

摘　　要：目的 :建立兔脑内血肿动物模型。方法 :家兔 16只平均分为 2组。采用二次注血法 ,首次注血 0 2ml,30min后注入其余血量 ,2组分别于 1d和 2d断头处死。用CT观察血肿形态并行病理检查。结果 :2组血肿体积及形态相对一致 ,能有效避免自体血从针孔溢出。结论 :以自体血并采用二次注血法制作的脑内血肿动物模型操作简单 。Aim: To establish the rabbit model of intracerebral hematoma. Methods: The method of double injection of self body blood was used.The first volume was 0.2 ml and the rest was injected after 30 min.The morphology of intracerebral hematoma was observed by computed tomography. Results: The method of double injection could effectively avoid self body blood overflowing from puncture pinhole .The size and morphology of intracerebral hematoma in 2 groups were relatively consistent. Conclusion: Using double injection to make intracerebral hematoma model is simple,convenient and reliable.

关 键 词：脑内血肿 兔 动物模型 

分 类 号：R651.15[医药卫生—外科学] R－332[医药卫生—临床医学]