毛果南烛叶的化学成分分析  

Study of chemical constituents from lyonia ovalifolia var hebecarpa

作　　者：王彩芳[1] 刘延泽[2] 李灿军[3] 陈绍农[3] 秦国伟[3] 

机构地区：[1]河南医科大学药学系,郑州450052 [2]河南中医学院中药系,郑州450008 [3]中国科学院上海药物所植化室,上海200031

出　　处：《河南医科大学学报》2001年第6期743-745,共3页Journal of Henan Medical University

摘　　要：目的 :研究杜鹃花科毛果南烛 (lyoniaovalifoliavarhebecarpa)叶的化学成分。方法 :体积分数为 95 %的乙醇提取物用溶剂划分部位 ,用柱色谱分离化合物 ,理化和波谱方法鉴定其结构。结果 :从毛果南烛叶中分离得到 3个化合物Ⅰ、Ⅱ和Ⅲ ,确定了它们的结构。Ⅰ命名为毛果南烛素甲 (lyohebecarpinA) ,同时酶水解得到其苷元Ⅰa ,命名为毛果南烛素甲苷元 (lyohebecarpiinA) ;Ⅱ、Ⅲ分别是β 谷甾醇和胡萝卜苷。结论 :Ⅰ、Ⅱ和Ⅲ均为首次从该植物中得到 。Aim: To study chemical constituents of leaf of lyonia ovalifolia var hebecarpa. Methods: Isolation of chemical constituents by Silica gel and RP C 18 column chromatography and identification by chemical and spectral methods.Results: Three compounds Ⅰ?Ⅱand Ⅲ were isolated.Ⅰ was identified and named as lyohebecarpin A .Ⅱand Ⅲ were β sitosterol and daucosterol respectively.The aglycone of Ⅰ,Ⅰa was named as lyohebecarpiin A.Conclusion: Ⅰ and Ⅰa is identified as a new compound ,Ⅱand Ⅲ were obtained from this plant for the first time.

关 键 词：毛果南烛 毛果南烛素甲 毛果南烛素甲钳元 提取 分离 结构鉴定 化学成分 

分 类 号：R284.1[医药卫生—中药学]