一锅法简便合成取代苯氧基苯乙酮  

Simple Synthesis of Substituted Phenoxy Acetophenone

作　　者：柳利[1] 陈祖兴[1] 杨桂春[1] 

机构地区：[1]湖北大学化学与材料科学学院,湖北武汉430062

出　　处：《合成化学》2001年第5期459-461,共3页Chinese Journal of Synthetic Chemistry

摘　　要：探讨了聚合物支载的铬 (Ⅵ )氧化剂、过溴离子及取代苯氧基离子于单锅中以 1 苯乙醇为底物 ,合成苯氧基苯乙酮的方法 ,并与分步合成法相比较。实验表明 ,此合成方法具有操作简便、反应条件温和、无须分离中间体、且产率较高等优点 ,并探索了温度、溶剂。Substituted phenoxy acetophenone was synthesized by one pot reaction of 1 benzyl alcohol with polymer supported chromic acid, bromine and substituted phenoxide. Comparing with the synthesis individually followed by isolation, it had mild reaction conditions and higher yields, avoiding the need to isolate the intermediaates. And we try detailed to find out the facts which influence the yields such as reaction temperature, solvents, and the quantity of resins.

关 键 词：取代苯氧基苯乙酮 一锅法合成 聚合物试剂 苯乙醇 

分 类 号：O625.42[理学—有机化学]