3-氨基-4-甲氧基乙酰苯胺合成新工艺  

A new Process for the Manufacture of 3-Amino-4-methoxy-acetanilide

作　　者：罗志强[1] 刘键[1] 申东升[1] 杨利文[1] 林源斌[1] 

机构地区：[1]湘潭大学化学化工学院

出　　处：《染料工业》2001年第5期28-29,22,共3页Dyestuff Industry

摘　　要：以2,4-二硝基氯苯为原料,经甲醇醚化先制得2,4-二硝基苯甲醚,再经Raney镍催化氢化得2,4-二氨基苯甲醚,不分离直接进行选择性酰化,合成出重要分散染料中间体3-氨基-4-甲氧基乙酰苯胺,品质稳定,全程收率大于80％。3-Amino-4-methoxy-acetanilide, an important intermediate for disperse azo dyes, was prepared by selective acylation of 2,4-diaminoanisole, which was synthesized by hydrogenation of 2,4-dinitroanisole in the presence of Raney Ni. 2,4-Dinitroanisole was produced from 2,4-dinitrochlorobenzene. The total yield was over than 80%.

关 键 词：3-氨基-4-甲氧基乙酰苯胺 RANEY镍 氢化 选择性酰化 合成 工艺 分散染料 中间体 

分 类 号：TQ612[化学工程—精细化工]