家兔脑干呼吸相关结构向斜方体后核的轴突投射──CB-HRP逆行示踪研究(英文)  

Afferent projection to the retrotrapezoid nucleus from respiratory related structures in the brainstem of rabbit—— A retrograde CB-HRP tracing study

作　　者：李勤[1] 宋刚[1] 

机构地区：[1]山东大学医学院生理教研室,济南250012

出　　处：《生理学报》2001年第5期401-404,共4页Acta Physiologica Sinica

基　　金：ThisresearchwassupportedbytheNationalNaturalScienceFoundationofChina (No 39970 2 78)

摘　　要：实验在 10只成年家兔上进行。斜方体后核 (RTN)内微量注入霍乱毒素 β亚单位耦合辣根过氧化酶 (CB HRP)后 ,在脑桥K lliker Fuse核、臂旁内侧核及臂旁外侧核观察到大量HRP标记神经元。在延髓孤束核腹外侧区、疑核和后疑核、面神经后核的腹侧及内侧区观察到少数HRP标记神经元。在面神经后核、疑核及后疑核区域观察到大量HRP顺行标记末梢纤维。实验结果表明 :RTN和脑桥及延髓的呼吸相关结构之间存在纤维联系。Experiments were performed on 10 adult rabbits. After microinjection of cholera toxin B subunit conjugated horseradish peroxidase (CB HRP) into the retrotrapezoid nucleus (RTN), retrogradely labeled neurons were mainly observed in the Klliker Fuse nucleus (KF), the medial parabrachial nucleus (PBM) and the lateral parabrachial nucleus (PBL). A few labeled neurons were also observed in the ventrolateral solitary tract nucleus, the ambiguus and retroambiguus nuclei, and the ventromedial area of retrofacial nucleus. Labeled terminal fibers were mainly observed in the retrofacial nucleus, the ambiguus and retroambiguus nuclei, the ventrolateral area of solitary tract nucleus, and the PBL PBM KF. The above results show that the RTN has axonal connections with the pontine and medullary respiratory related structures.

关 键 词：斜方体后核 Koelliker-Fuse核 臂旁内侧核 CB-HRP 呼吸 相关结构 脑干 神经纤维 投射 

分 类 号：R338[医药卫生—人体生理学]