N_3质粒对λ噬菌体发育途径的影响  

The Influence of Plasmid N_3 on λ Phage Deveiopment Pathway

作　　者：许华[1] 蒲蔷[1] 赵叙梅 张永地[1] 

机构地区：[1]中国科学院成都生物研究所

出　　处：《病毒学杂志》1989年第2期182-187,共6页

摘　　要：诱导试验表明N_3质粒抑制λ溶源菌诱导处理时的裂解性发育途径,使λ噬菌体产率大大降低,仅为对照的10^(-5)—10^(-6)。感染实验表明N_3质粒主要抑制λ噬菌体的溶源性发育途径,其溶源菌形成率仅为对照的1.3—1.9％。从N_3质粒对λ噬菌体感染时与λ溶源菌诱导时的发育途径的不同作用的事实推测N_3质粒的某种产物(蛋白质)与λ噬菌体cI蛋白相作用,以障碍cI蛋白正常解离或聚合的方式而干扰其发育途径。Plasmid N_3 inhibits inductive development in λ lysogen. It makes λ yield lower 10^(-5)—10^(-6) times than that of the contiol. Plasmid N_3 inhibits λ lysogenic development pathway on λ infection. Tire inhibition mechanism of λ development by plasmid N_3 is supposed that the polymerization and depolymerization of λ cI proteins is blocked by the interaction between λ cI protein and plasmid N_3 (probably, plasmid N_3 protein(S)).

关 键 词：Λ噬菌体 N3质粒 流产发育 

分 类 号：Q939.48[生物学—微生物学]