维C银翘片中对乙酰氨基酚和维生素C的HPLC测定  

Determination of Paracetamol and Vitamin C in Wei C Yinqiao Tablets by HPLC

作　　者：尤卫民 吴韶铭 

机构地区：[1]金华市药品检验所,浙江金华321000

出　　处：《中成药》2001年第8期565-566,共2页Chinese Traditional Patent Medicine

摘　　要：目的 :建立维C银翘片中对乙酰氨基酚和维生素C的HPLC测定方法。方法 :采用C18柱 (4 .6× 2 5 0mm ,5 μm) ,0 .0 2mol/L磷酸二氢钾 乙腈 (90∶10 )为流动相 ,检测波长为 2 49nm。结果 :平均回收率为 :对乙酰氨基酚 10 0 .5 % (RSD =1.33% )、维生素C98.7% (RSD =1.6 8% )。结论 :该方法简便、快速、准确 。Objective: To establish a HPLC for determination of paracetamol and vitamin C in Wei C Yinqao Tablets. Methods: A Hypersil C 18 column(4.6×250mm,5μm) was used with a mobile phase of 0.02mol/L potassium dihydrogen phosphate acetonitrile (90∶10). The detection wavelength was 249nm. Results: The average recoveries of paracetamol and vitamin C were 100.5%(RSD was 1.33) and 98.7%(RSD was 1.68%), respectively. Conclusion: The method is simple, rapid and accurate. It can be used for quantitative analysis of Wei C Yinqiao Tablets.

关 键 词：维C银翘片 对乙酰氨基酚 维生素C HPLC 质量控制 中药 

分 类 号：R286.0[医药卫生—中药学]