枳椇子酒与枳椇子水提取液解酒毒作用比较研究  

Comparing Study of Detoxification Effects of Wine and Aqueous Extract of Hovenia dulcis Thunb. on Acute Alcohol Toxicity in mice

作　　者：嵇扬[1] 陆红 杨平[3] 

机构地区：[1]中国人民解放军总后勤部卫生部药品仪器检验所,北京100071 [2]沈阳空军医院,辽宁沈阳110042 [3]中国人民解放军532医院,安徽黄山245000

出　　处：《时珍国医国药》2001年第6期481-483,共3页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 :比较枳子酒与枳子水提取液解酒毒作用。方法 :考察醒酒时间、乙醇浓度、丙二醛含量、谷胱甘肽过氧化物酶活力。结果 :枳子水提取液可明显缩短乙醇诱导的小鼠睡眠时间 ,降低血中乙醇的浓度 ,降低丙二醛含量并能提高谷胱甘肽过氧化物酶活力 ;枳子酒作用不显。结论 :枳子水提取液具解酒毒功效。Objective:To compare the detoxification effects of wine and aqueous extract of Hovenia dulcis Thunb. (HDT) on acute alcohol toxicity in mice.Methods:To investigate sleeping time, alcohol concentration, MDA content and GSH-Px activity.Results:Aqueous extract of HDT can shorten sleeping time induced by alcohol, decrease alcohol concentration, reduce MDA content and increase GSH-Px activity significantly. The wine of HDT can not significantly improve indexes above.Conclusion:The aqueous extract of HDT hsa the effects of relieving alcohol toxicity.

关 键 词：枳JU子 酒精中毒 脂质过氧化损伤 小鼠 

分 类 号：R285.5[医药卫生—中药学]