光谱法及热动力学法研究环糊精与四—N—正丙基吡啶基卟啉的作用  

A Study on Inclusion Complexes of Cyclodextrins with 5,10,15,20- Tetrakis(4- propylpyridinium) porphyrin Bromide by Spectral Analysis and Thermodynamics

作　　者：杨频[1] 范晓毅[1] 陈世荣[1] 韩高义[1] 

机构地区：[1]山西大学分子科学研究所,

出　　处：《化学学报》2001年第10期1550-1556,共7页Acta Chimica Sinica

基　　金：国家自然科学基金

摘　　要：通过紫外吸收,荧光光谱,一维、二维核磁共振技术等光谱方法,确定了环糊精与四-N-正丙基吡啶基卟啉2:1型包合物的形成,分子模拟方法进一步证实了该包合物的形成;采用热动力学法研究了温度对包合反应的影响,计算得出包合过程的熵变、焓变及自由能变化,绘出了卟啉类化合物与环糊精包合物的熵焓补偿曲线,进而确定了包合反应的主要驱动力是焓.The inclusion complexes of cyclodextrins with 5, 10, 15, 20 - tetrakis (4 - propylpyridinium) porphyrin bromide were confirmed by UV, fluorescence spectra and NMR, respectively. The molecular modeling provided further evidence for the formation of the inclusion complexes. The effect of temperature on the reaction was studied through thermodynamics. The changes of entropy, enthalpy and free energy of the reaction were calculated and the entropy - enthalpy compensation plot of the inclusion complexes of porphyrin and CyDs was then studied, which led to the conclusion that enthalpy is the main impetus for the inclusion reaction.

关 键 词：环糊精 四-N-正丙基吡啶基卟啉 包合物 光谱分析 分子模拟 热动力学 超分子 

分 类 号：O641.3[理学—物理化学] O626.13[理学—化学]