围绝经期妇女血清瘦素水平的测定及其意义  

The Detection of Serum Leptin in Perimenopausal Woman

作　　者：魏涛[1] 陈艳萍 马永秀[1] 何娟[1] 

机构地区：[1]青岛市市立医院放免中心,山东青岛266011 [2]青岛市儿童医院检验科,山东青岛266011

出　　处：《标记免疫分析与临床》2001年第3期129-131,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：本文采用放射免疫测定法 (RIA)检测了 138例围绝经期妇女 (其中月经紊乱期 81例 ,绝经期 5 7例 )血清FSH、LH、E2 、瘦素水平 ,并与 4名育龄妇女各项指标对照比较。在此基础上探讨它们在围绝经期妇女正常生理过程中的相互关系。结果表明 :瘦素在月经紊乱期妇女 (P <0 .0 5 )和绝经期妇女 (P <0 .0 1)中都有较明显变化 ;FSH、LH、E2 亦有显著变化 (P <0 .0 1) ,提示瘦素参与了围绝经期妇女的正常生理变化 。Serum leptin, follicle stimulating hormone(FSH), luteinizing hormone(LH) and estradiol(E 2) were measured by RIA in 138 perimenopausal women in order to clear the relations between them. The result showed that serum levels of all the four circulating hormones are all changed significantly in all subgroups. Compared with the women of childbearing age group, it changed with P<0.05; P<0.01 respectively. All the changes indicate: As a circulating hormone, leptin plays an important role in woman's normal physicology developing process along ages.

关 键 词：放射免疫测定法 围绝经期 瘦素 

分 类 号：R335[医药卫生—人体生理学]