2型糖尿病患者血清肿瘤坏死因子和唾液酸检测的临床意义  

Measurement of Serum TNF and SA in Patients with NIDDM and Their Clinical Significance

作　　者：何浩明[1] 黄慧建[1] 徐宁[1] 田小平[1] 苏彩女[1] 徐凤英[1] 

机构地区：[1]江苏省连云港市第一人民医院,江苏连云港222002

出　　处：《标记免疫分析与临床》2001年第3期145-146,共2页Labeled Immunoassays and Clinical Medicine

摘　　要：分别应用放射免疫分析法和分光光度计法检测了 35名正常人和 82例 2型糖尿病患者血清中肿瘤坏死因子 (TNF)和唾液酸 (SA)含量。结果表明 :2型糖尿病患者无肾病组和伴有肾病组血清中TNF和SA含量均非常显著地高于正常人 ,尤以伴有肾病组为甚 (P <0 .0 0 1)。这说明The levels of serum TNF and SA were detected in 82 patients with NIDDM and 35 normal controls. The results shouwed that the levels of TNF and SA in NIDDM group were obviously higher than those in normal control(P<0.01), particularly in NIDDM with nephrosis group(P<0.001).It′s suggested that the concentration of TNF and SA is relevant to the pathogenesis of NIDDM.

关 键 词：Ⅱ型糖尿病 肿瘤坏死因子 唾液酸 放射免疫分析法 分光光度计法 TNF 

分 类 号：R587.1[医药卫生—内分泌]