解冻后活动精子总数对他精人工授精妊娠率的影响研究  

Effect of Total Motile Spermatozoa Number After Thawing on AID Pregnancy Rate

作　　者：范立青[1] 朱文兵[1] 肖红梅[1] 曾亚荣[1] 卢光琇[1] 

机构地区：[1]中南大学湘雅医学院人类生殖工程研究室,湖南长沙410078

出　　处：《中国医师杂志》2001年第9期572-573,578,共3页Journal of Chinese Physician

基　　金：湖南省自然科学基金 (99JJY-20030)项目;973(G1 9990 5590 1)项目资助

摘　　要：目的　探讨在他精人工授精 (AID)过程中 ,解冻后活动精子总数与AID妊娠率的关系。方法　回顾了我室精子库数据库管理系统的资料 ,比较解冻后活动精子 (A、B级 )总数对AID妊娠率的影响。结果　治疗周期中排卵前后两次授精活动精子总数均 <30× 10 6,和均≥ 30× 10 6相比 ,其妊娠率分别为 10 4 5 %和 2 6 4 9% ,在统计学上有显著性的差异 (P <0 0 1) ;若排卵前授精≥ 30× 10 6,排卵后 <30× 10 6,其妊娠率为 18 90 % ,与上述两组相比在统计学上亦有显著性的差异 (P <0 0 1)。结论　用于人工授精的冻融精液需要有 30× 10 6以上的活动精子 (A、B级 ) 。Objectives To study the relationship between total motile spermatozoa number after thawing and pregnancy rate in artificial insemination with donor's semen(AID). Methods By a retrospective survey on data in our sperm bank, we studied influences of total motile spermatozoa number(A,B grade) on AID pregnancy rate.Results We compared the two groups of total motile spermatozoa number <30×10 6 and≥30×10 6 in two insemination cycle before and after ovulation and found the pregnancy rates were 10.45% and 26.49%, respectively. There was statistical difference (p<0.01).The group with total motile sperm number before ovulation ≥30×10 6 and that after ovulation <30×10 6 had a pregnancy rate of 18.90%, there was also statistical difference from the other two groups(p<0.01).Conclusions Above 30×10 6 total motile sperms (A,B) are required for thawed semen in AID. The importance of definite total motile spermatozoa number is simlar both in insemination before and after ovulation.

关 键 词：人工授精 冷冻精液 精子 妊娠率 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学]