山东省十地市人轮状病毒分子流行病学研究  

Molecular Epidemiology of Human Rotavirus in Ten Cities of Shandong Province in China

作　　者：王英才[1] 邵济钧[1] 臧云娟[1] 

机构地区：[1]青岛医学院微生物学教研室

出　　处：《病毒学杂志》1989年第4期359-364,共6页

摘　　要：用核酸凝胶电泳法对1985—1986年山东省十地市的318份婴幼儿急性腹泻粪便标本中测出的170份HRV阳性标本作了RNA电泳型分析,发现3个地区为HRVI亚群流行,3个地区为HRVⅡ亚群流行,4个地区为两亚群共同流行,共检出差异电泳型34个,其中14个属长RNA电泳型,20个属短RNA电泳型。在一个地区虽有多个差异电泳型毒株流行,但仅有其中的1—2个占流行优势。在两亚群毒株共同流行区,检出的差异电泳型特别多。本文并对HRV RNA电泳型多形性的原因及意义进行了讨论。Using the PAGE method, we analysed the electrophoretic types of RNA rotavirus obtained from 170 stool samples with infantile diarrhea from ten cities in Shandao from 1985—1986, In 3 cities subgroup Ⅰ rotavirus was found to be the main etiologic agent, subgroup Ⅱ in other 3 cities and both subgroups were found prevailing in the rest cites. Among 34 different electrophoretic typs observed, 14 belong to subgroup Ⅰ and 20 to subgroup Ⅱ。In the cities with two subgroups co-prevailing, there were far more electrophoretic types found than in the cities with only one subgroup. The significance of the genetic diversity of the rotavirus genome is also discussed.

关 键 词：轮状病毒 流行病学 电泳图形 

分 类 号：R512.501[医药卫生—内科学]