用正交设计法选择高效液相色谱法测定血浆去甲肾上腺素的试验条件  

CHOOSING TEST CONDITIONS WITH ORTHOGONAL DESIGN METHOD FOR DETERMINING PLASMA NOREPINEPHRINE USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

作　　者：张林[1] 栗建民[1] 陈日新[1] 

机构地区：[1]南京铁道医学院医学系内科心血管研究室

出　　处：《南京铁道医学院学报》1991年第3期177-181,共5页Journal of Nanjing Railway Medical College

摘　　要：利用正交设计法对高效液相色谱法测定血浆去甲肾上腺素的条件进行整体设计,并对试验结果进行详细的统计分析。结果表明原来要做108次(3~3+3~4)试验减少到36次。本法对高效液相色谱法测定微量物质的条件选择有一定参考和使用价值。An integrated design of test conditions was made for determining plasma norepi- nephrine with high performance liquid chromatography using orthogonal design method. A detailed analysis of parameters obtaind showes that a satisfactory result may be obtained with only 36 tests as compared with 108 (3~3+4~3)tests before.This design will certainly have a reference and application value in choosing conditions for deter- mining trace materials with high performanca liquid chromatography.

关 键 词：正交设计 去甲肾腺素 液相色谱 

分 类 号：R446.112[医药卫生—诊断学]