二尖瓣球囊扩张术后远期心功能储备变化的随访观察  

Changes in cardiac function reserve after percutaneous balloon mitral valvuloplasty: a long term follow-up study

作　　者：傅向阳[1] 彭献波[2] 吕俊豪[1] 叶文胜[1] 傅强[1] 赵霞[1] 

机构地区：[1]第一军医大学珠江医院心内科,广东广州510282 [2]西藏军区总医院内四科,西藏拉萨850003

出　　处：《第一军医大学学报》2001年第11期855-857,共3页Journal of First Military Medical University

摘　　要：目的 探讨二尖瓣储备功能在经皮球囊二尖瓣成形术（ＰＢＭＶ）之后和长期随访中的变化及与负荷超声心动图积 分的关系，以预测ＰＢＭＶ远期疗效。方法　对二尖瓣狭窄患者静脉滴注异丙肾上腺素提高心率，模拟轻、中、重度体力活 动，分别于术后、随访期采用超声心动图观察心功能各项指标，并于术前进行Wilkins积分，术后进行负荷超声心动图 积分。结果　ＰＢＭＶ术后二尖瓣储备、心功能储备部分恢复。负荷超声心动图积分与远期心功能相关性良好（ｒ＝－０．８２）。 结论ＰＢＭＶ术导致二尖瓣面积增大同时其储备功能部分恢复。负荷超声心动图积分较Wilkins积分对远期心功能的 评价具有更大价值。Objective To evaluate the long-term effect of percutaneous balloon mitral valvuloplasty (PBMV) by observing the changes in mitral valve reserve after PBMV and during the long-term follow-up and by exploring the relations of these changes with stress echocardiographic scores. Methods Stress echocardiogaphy was performed in patients receiving PBMV for mitral stenosis both after surgery and during the long-term follow-up study, and Wilkins scores of the patients were obtained pre-operatively. Intravenous isoproterenol was administered before test to increase the heart rate to simulate mild, moderate and heavy exercises, and the indices for cardiac function were recorded. Results After PBMV, mitral valve reserve and cardiac function reserve were partly restored, and stress echocardiographic score was closely related to long-term cardiac function (r=-0.82). Conclusions PBMV can increase mitral valve area and partly restore funtional reserve, and stress echocardiographic score is more predictive of the long-term cardiac function than Wilkins score.

关 键 词：经皮球囊二尖瓣皮形术 二尖瓣储备 负荷超声心动图 积分 PBMV 

分 类 号：R542.51[医药卫生—心血管疾病]