人参二醇组皂甙对游泳训练大鼠抗氧化效应及免疫调节的研究  

EFFECT OF PANAXADIOL SAPONINS ON ANTI-OXIDIZATION AND IMMUNOLOGIC REGALATION IN LONG-TERM SWIMMING TRAINING RATS

作　　者：王密[1] 许明荣[2] 杨柯[3] 孟艳[3] 赵丹[3] 

机构地区：[1]广西卫生管理干部学院病理学教研室,南宁530021 [2]广西大学体育部 [3]吉林大学新民校区病理生理学教研室

出　　处：《广西医科大学学报》2001年第4期479-481,共3页Journal of Guangxi Medical University

摘　　要：目的 :观察人参二醇组皂甙 (PDS)对长期游泳训练大鼠模型抗氧化及免疫调节效应。方法 :1检测大鼠肺、肝、肾、心、骨骼肌、红细胞及血清超氧化物歧化酶 (SOD)与脂质过氧化物 (L PO)的水平变化 ;2淋巴细胞转化实验与胸腺细胞自发增殖反应。结果 :PDS可以降低肝、肾、心与骨骼肌组织中 L PO的水平 ,提高红细胞与肺组织中 SOD的活性 ,作用的范围大于甲基睾酮 ,而且对运动后胸腺细胞自发增殖反应的恢复有促进效应。结论 :PDS对于自由基与 L PO引起的运动性疲劳和损伤防治有重要意义 。Objective: To study effect of Panaxadiol sapoins (PDS) on an ti -oxidization and regulation of immunology in an endurance swimming training mode l Methods:We establish the long term swimming training model of rats, and detect the two sorts index as the fellows:①the levels of superoxide dismutase (SOD),lipid peroxide (LPO) of the serum,red blood cell,heart,lung,liver,renal and skeletal muscle;②the arrays of cell immunology include test of lymphocyte conversion and thymocyte auto-proliferation reaction Results:The level s were significantly decreased in the tissue of heart,liver,renal and skeletal muscle,a significant increase in SOD of red blood cell and lung.In addition, PDS can accelerate increase of thymocyte auto-proliferation reaction after the endurance swimming training Conclusion: PDS may be applied to treat sports fat igue and injury induced by LPO,and strengthens the immunologic function of endurance training rats

关 键 词：人参二醇组皂甙 超氧化物岐化酶 脂质过氧化物 免疫调节 游泳训练 大鼠 

分 类 号：G804.7[文化科学—运动人体科学] R285.5[文化科学—体育学]