肝复乐治疗肝炎肝硬化52例近期疗效观察  

Clinical Observation of a Short Term GFL Therapy for 52 Cases of Hepatitis with Liver Cirrhosis

作　　者：李武[1] 黄学惠[1] 唐宝璋[1] 杨微波[1] 游晶[1] 

机构地区：[1]昆明医学院第一附属医院,昆明650032

出　　处：《中西医结合肝病杂志》2001年第6期331-332,共2页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

摘　　要：探讨肝复乐片治疗肝炎肝硬化的临床疗效。方法:101例肝炎肝硬化患者,随机分为治疗组52例.对照组49例,两组均给予常规综合治疗,治疗组加用肝复乐片口服,每次6片,Tid,疗程8W。结果:治疗组乏力、纳差、腹胀、肝区不适等症状的改善较对照组快,降ALT、AST和消除AFP异常作用明显(P<0.05);该药还有一定的利尿作用,有助于肝硬化患者的腹水消退。但两组治疗前后肝大、脾大及HBV-M的变化无显著性差异(P>0.05)。综合疗效:治疗组(92.31％)显著优于对照组(77.55％)(P<0.05),其中,代偿性肝硬化治疗组明显优于对照组(P<0.05),而失代偿性肝硬化治疗组亦优于对照组,但统计学检验未见显著性差异(P>0.05)。未见明显不良反应。结论:肝复乐片可作为肝炎肝硬化综合治疗中的一种较好选择。To observe the therapeutic effect of GFL (Gan Fu Le) in the treatment of hepatitis liver cirrhosis. Method: 101 patients with hepatitis liver cirrhosis were randomly divided into treatment group (52 cases) and control group (49 cases). The same synthesis therapy was applied to the two groups routinely. GFL was given orally in a three times a day dose of 6 tablets for 8 weeks. Results: The total efficiency was 92.31% in the treatment group, and 77. 55% in the control group (P<0. 05). The symptoms (weakness,anorexia,upper abdominal discomfort and abdominal distension) of treatment group was improved more rapidly than that of control group. The effect of ALT, AST, AFP return to normal were obviously. There was no significant adverse reaction. Conclusion: GFL was an effective and safe drug for the synthesis therapy of hepatitis liver cirrhosis.

关 键 词：肝炎肝硬化 肝复乐片 疗效 中医药疗法 

分 类 号：R259.7[医药卫生—中西医结合]