金菊花乙酸乙酯提取物对大鼠实验性肝损伤的影响  

Effect of Ethyl Acetate Extract of Dendranthema Morifolium on Experimental Liver Injury of Rats

作　　者：芦金清[1] 李竣[1] 彭少平[1] 刘毅[1] 

机构地区：[1]湖北中医学院,武汉430061

出　　处：《中西医结合肝病杂志》2001年第6期345-346,共2页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

摘　　要：观察金菊花乙酸乙酯提取物(EAEDM)对肝损害的防护作用。方法:建立大鼠急性乙醇中毒肝损害模型,通过大鼠灌胃EAEDM,以对照组对照,测定血清过氧化脂质(MDA)、谷胱甘肽过氧化物酶(GSH-PX)、血清谷丙转氨酶(ALT)和血清谷草转氨酶(AST)的含量。结果:EAEDM能降低MDA、ALT和AST的活性,减少肝脏MDA的生成,增加GSH-PX的活性。结论:EAEDM对肝损伤具有防护作用。To observe the protective action of ethyl acetate extract of Dendranthema Morifolium on liver injury in rats. Methods: In this study, the acute ethylism rat model was used. Results: The ethyl acetate extract of Dendranthema Morifolium could inhibit the activities of MDA, ALT, AST; decrease the formation of MDA in liver; increase the activity of GSH-PX. Conclusion: The ethyl acetate extract of Dendranthema Morifolium have protective action on liver injury.

关 键 词：乙酸乙酯提取物 金菊花 急性乙醇中毒 大鼠模型 肝损伤 中药 药理 

分 类 号：R285.5[医药卫生—中药学]