肺炎衣原体和冠心病关系的研究  

Relationship between chlamydia pneumoniae and coronary heart disease

作　　者：董平栓[1] 刘煜昊[1] 付朝红 杨旭明[1] 宋润珞[1] 来艳丽[1] 刘福喜[1] 

机构地区：[1]洛阳医学高等专科学校附属医院,471003

出　　处：《中国综合临床》2001年第7期500-501,共2页Clinical Medicine of China

摘　　要：目的研究肺炎衣原体和冠心病的关系。方法在非冠心病 (NCHD)组、稳定型心绞痛 (SAP)组、不稳定型心绞痛 (UAP)组和急性心肌梗死 (AMI)组 ,用血清学和 PCR方法检测肺炎衣原体。结果各组之间血清学无显著性差异。冠心病各组 PCR阳性率显著高于NCHD组 ,UAP、AMI两组间差异无显著性意义。Objective To study the relationship between chlamydia pneumoniae and coronary heart disease.Methods Serology and PCR for detecting chlamydia pneumoniae were conducted in groups of non coronary heart disease(NCHD),stable angina pectoris(SAP),unstable angina pectoris(UAP)and acute angina pectoris(SAP),unstable angina pectoris(UAP)and acute myocardial infarction(AMI).Results No significant difference was found in serology among each group.The positive rate of PCR of CHD group was higher than that of CHD group,and the positive rates of PCR of both UAP and AMI were higher than that of SAP group.There was no significant difference between the positive rates of PCR of UAP and AMI group.Conclusion Chlamydia pneumoniae contributes to the formation of coronary heart disease and the ustability of plaque.

关 键 词：肺炎衣原体 冠心病 聚合酶链反应 诊断 

分 类 号：R541.4[医药卫生—心血管疾病]