家族性Graves病55例临床分析  

The clinical characteristics of familial Graves' disease

作　　者：陈德才[1] 陈霞[1] 张东玲[1] 贾卫国[1] 魏松全[1] 

机构地区：[1]华西医科大学附属第一医院内分泌科,成都610041

出　　处：《临床内科杂志》2001年第4期298-299,共2页Journal of Clinical Internal Medicine

摘　　要：目的　分析家族性Graves病 (GD)的临床特征 ,并与同期住院的非家族性GD进行比较。方法　对同期住院的 5 5例家族性GD和 471例非家族性GD的临床特征进行回顾性对比分析。结果　家族性GD约占全部GD的 10 % ;病程较长 ;男女患病机会相等 ;复发和发生浸润性突眼的相对危险度分别是非家族性GD的 2 .3倍和 2 .1倍。结论　家族性GD具有男女患病机会一致、容易复发。Objective To analyze the clinical characteristics of patients with familial Graves' disease(GD) and compare with that of non familial GD patients in the same time. Methods Medical records of 55 patients with familial GD and 471 patients with non familial GD in the same period were retrospectively reviewed, and comparison of clinical characteristics between two groups was made. Results (1) About 10 percent of these patients were familial GD. (2) The chance suffering from familial GD was equal between different sex. (3) Recurrence and combinatoin of malignant exophthalmos risk ratio of familial GD was 2.3 folds and 2.1 folds compared with non familial GD respectivly. (4) The duration was longer in patients with familial GD than that of non familial GD. Conclusion In clinic, familial GD was characterized by the equal chance between male and female, be prone to recur and longer course of disease than that of non familial GD.

关 键 词：GRAVES病 家族丛聚 发病机理 诊断 治疗 

分 类 号：R581.1[医药卫生—内分泌]