密骨胶囊合丙酸睾丸酮治疗骨质疏松症疗效观察  

Observation of Therapeutic Effect of Osteoporosis Treated by"Bone Density Capsules"and Testosterone

作　　者：许理忠[1] 石印玉[1] 谢可永[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海,200032

出　　处：《上海中医药大学学报》2001年第3期24-25,共2页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：国家"九.五"中医药科技攻关项目 (96 - 90 6 - 0 9- 0 5 )

摘　　要：为观察中药密骨胶囊对骨质疏松症的作用 ,将原发性骨质疏松症患者 10 0例随机分成治疗组 6 0例、对照组 40例。治疗组口服中药密骨胶囊 (每日 2次 ,每次 2粒 ) ,并肌肉注射丙酸睾丸酮 (每次 2 5mg ,每周 2次 ) ,3个月为一疗程 ;疗程结束后 ,停用丙酸睾丸酮 ,续服中药 ,2个月后再行第 2个疗程。对照组用补钙剂或镇痛剂对症治疗。 8个月后分别统计骨痛改善程度、骨密度值。结果 :疼痛改善优良率治疗组为 73 3% ,对照组为 30 .0 % ;骨密度值增加或不变率治疗组为 5 6 7% ,对照组为 10 .0 % ;治疗组均优于对照组 (P <0 0 1;P <0 0 5 )In order to observe the function of 'Bone Density Capsules'on osteoporosis,100 cases of primary osteoporosis were randomly divided into 60 cases of the treatment group and 40 cases of the control group.In the treatment group,'Bone Density Capsules'were given for oral administration(twice a day,2 capsules each time)and intramuscular injection of testosterone propionate(25mg each time,twice a day)for three months as one course of the treatments.After the course of the treatments,testosterone propionate was stopped,but Chinese medicine was still used.The second course of the treatments started after two months.In the control group,the treatments were given upon the symptoms with calcium and analgesics.After eight months,the improving degree of bone pain and bone density value were respectively checked.The results showed that the excellent rate in improving pain was 73 3% in the treatment group and 30.0% in the control group and that the increasing rate or no change of the bone density value was 56 7% in the treatment group and 10.0% in the control group,indicating that the treatment group was better than the control group( P<0 01;P <0 05).

关 键 词：密骨胶囊 丙酸睾丸酮 骨质疏松症 疼痛 骨密度 

分 类 号：R58[医药卫生—内分泌]