幼儿腹泻血清维生素A、维生素E含量研究(附41例检测报告)  

作　　者：郑兴华[1] 彭维林[2] 

机构地区：[1]福建医科大学附属第二医院,362000 [2]泉州市儿童医院,362000

出　　处：《福建医药杂志》2001年第4期18-19,共2页Fujian Medical Journal

摘　　要：目的　通过对幼儿腹泻患者血清维生素 A和维生素 E含量测定 ,探讨其与腹泻相互关系 ,为临床防治提供参考。方法　采用反相高效液相色谱法 ,同时测定维生素 A、维生素 E含量 ,对 41例幼儿腹泻患儿进行检测 ,并与同期 41例体检健康幼儿对照。结果　幼儿腹泻组的血清维生素 A均值 (0 .72± 0 .2 9μmol/ L)明显低于健康组 (1.2 5±0 .37μmol/ L) (U=197,p<0 .0 0 1) ,亚临床维生素 A缺乏及可疑诊断的检出率明显高于健康对照组 (X2 =37.6 98,P<0 .0 0 1)。幼儿腹泻组与健康对照组维生素 E水平分别为 8.97± 4.6 4μmol/ L、 14.42± 3.78μmol/ L ,两组比较 ,差别有非常显著意义 (t=5 .834,p<0 .0 0 1)。结论　幼儿腹泻组血清维生素 A、维生素 E水平均低于健康者 ,而维生素 A亚临床缺乏及可疑诊断高于健康幼儿 ,提出补充维生素 A对防治幼儿腹泻很有必要 ,同时适当补充维生素Objective To study the levels of serum vitamin A and vitamin E in infantile with diarrhea.Methods:In 41 cases with infantile diarrhea and 41 cases controls,serum vitamin A and vitamin E level were simultaneously determined by RP HPLC method.Results The serum Vitamin A levels of the cases with infantile diarrhea and healthy infants were 0 72±0 29 μ mol/L and 1 25±0 37μ mol/L,respectively(U=197,p<0 001).The incidences of preclinical vitammin A deficiency,dubious diagnosis were 53 7%,34 1% and 2 4%,24 4% respectively(x 2=37 698,p<0 001).The levels of serum vitamin E of the cases with infantile diarrhea and healthy infants were 8 97±4 64 μ mol/L and 14 42±3 78 μ mol/L,respectively(t=5 834,p<0 001),Conclusions It was suggested that the serum vitamin A or vitamin E level of infants with diarrhea were clearly lower than that of the healthy infants,and the incidence of preclinical vitamin A deficiency was significantly higher than that of the healthy control group.

关 键 词：婴幼儿腹泻 维生素A 维生素E 含量 血清 

分 类 号：R725.7[医药卫生—儿科]