胚胎骨骨基质明胶移植的实验研究  

An Experimental Study of Embryonic Bone Matrix Gelatin Transplantation

作　　者：曾昭源[1] 张永福 郑坚 

机构地区：[1]南昌附属口腔医院口腔外科,南昌330006 [2]南昌附属口腔医院病理科,南昌330006

出　　处：《江西医学院学报》1998年第3期27-29,共3页Acta Academiae Medicinae Jiangxi

摘　　要：根据Urist等人的方法制备人胚胎骨全脱钙和部分脱钙骨基质明胶（bonematrixgelatin，BMG），同时采用这两种材料修复家兔下颌骨体部1cm×0．5cm大小全层缺损，以自体骨移植和未植骨作对照，通过大体观察，X线观察和组织学切片来评价修复效果，结果显示：植骨组与自体骨移植组修复较好，与未植骨组比较差异有显著意义。说明胚胎骨BMG是一种可供选择的骨修复材料。Completely and partially decalcified human embryonic bone matrix gelatin (BMG) wasprepared according to Urist’s methods and used to repair rabbits’ mandibular defects (1 cm×0. 5 cm). Rabbits with autografts and without grafts were used as controls. The effects wereevaluated by naked eyes, x-ray and histological sections. The results showed: Bone defectstreated with BAG or autografts were repaired well,having significant difference from thosewithout grafts. It is suggested that embryonic bone matrix gelatin is a material of choice torepair bone defects.

关 键 词：胚胎 骨诱导活性 骨组织 骨移植术 BMG 颌骨缺损 兔 

分 类 号：R687.34[医药卫生—骨科学]