急性心肌梗死的心室复极时间变异性研究  

Ventricular Repolarization Duration Variability Measurment after Acute Myocardial Infarction

作　　者：曲秀芬[1] 刘莹[1] 黄永麟[1] 苗润芳[1] 纪树彦[1] 高冠宇[1] 苏雅芬[1] 朴晶燕[1] 张卓琦[1] 杜晓东[1] 

机构地区：[1]哈尔滨医科大学附属第一医院心内科,黑龙江省哈尔滨市150001

出　　处：《中国循环杂志》2001年第5期351-353,共3页Chinese Circulation Journal

基　　金：卫生部科研基金资助课题

摘　　要：目的 :研究正常人及急性心肌梗死患者的心室复极时间变异性 (RDV)。　　方法 :对 30例急性心肌梗死患者 (急性心肌梗死组 )及 30例健康人 (正常对照组 ) ,采用 2 4小时动态心电图监测系统进行记录 ,同步分析RDV及心率变异性 (HRV )。　　结果 :①正常对照组高频、低频显示出明显的昼夜节律性变化 ,夜间明显高于白昼 (P <0 0 5 )。②急性心肌梗死组患者的SDNN、SDANN、高频、低频均低于正常对照组 ,有显著差异 (P <0 0 5 ) ,且失去了昼夜间差异。③RDV的频谱分析呈现出与HRV相似的两个主要的频谱成分即高频和低频。高频在正常人RDV与HRV有较好的相关性 (γ=0 82 ,P <0 0 1) ,而在急性心肌梗死患者此相关性降低 (γ =0 6 1,P <0 0 5 )。　　结论 :RDV提供了又一无创方法评价心室复极的自主神经调节机制 ,可对心肌梗死患者的恶性心律失常进行预测。Objective:To investigate ventricular repolarization duration variability (RDV) both in normal individuals and in patients with acute myocardial infarction(AMI). Methods:RDV analysis of 24-hour Holter tapes was performed in 30 patients and 30 normal individuals.After pre-processing of digitized 24-hour Holter ECGs,heart rate variability and repolarization duration variability were analysed. Results:①In normal individuals,the circadian variation existed significantly in ventricular repolarization(RD)?high frequency (HF) and low frequency (LF).②All values of RDV in AMI were significantly low compared with the controls (p<0.05),and circadian variation was disappeared.③In normal individuals,the frequency contents of the RDV and HRV are qualitatively very similar. Conclusion:RDV may provide an additional noninvasive tool to evaluate the neural mechanisms regulating ventricular repolarization.It may be predictive for malignant arrhythmias in patients after AMI.

关 键 词：急性心肌梗死 心室复极时间变异性 心率变异性 

分 类 号：R542.22[医药卫生—心血管疾病]