冬虫夏草制剂延缓慢性肾衰竭的机理研究  

Study of Cordyceps on mechanism in delaying chronic renal failure

作　　者：邓跃毅[1] 陈以平[1] 贺学林[1] 李莉[1] 

机构地区：[1]上海中医药大学附属龙华医院肾科,上海200032

出　　处：《中国中西医结合肾病杂志》2001年第7期381-383,共3页Chinese Journal of Integrated Traditional and Western Nephrology

摘　　要：目的 :为探讨冬虫夏草制剂治疗慢性肾衰竭的机理。方法 :采用 5 / 6肾切除大鼠CRF模型 ,观察治疗后的大鼠血脂、中分子物质等。结果 :发现可降低CRF大鼠血膦、升高血钙、降低中分子物质、改善贫血状态、纠正脂质代谢紊乱。结论 :冬虫夏草制剂延缓慢性肾衰竭进展的机理可能与降低中分子物质、纠正脂质代谢紊乱、改善贫血有关。Objective: To study the mechanism of cordyceps in delaying chronic renal failure. Methods: The rat model with 5/6 nephrectomy was employed to observe the effects of cordyceps on blood fat, middle molecule substance (mms) ets.Results:cordyceps decreased serum phosphorus and MMS,increased serum calcium,ameliorated renal anemia and improved lipid metabolic disorder.Conclusion:The mechanism of cordyceps in delaying chronic renal failure is related to decreasing MMS,ameliorating renal anemia and improving lipid metabolic disorder.

关 键 词：冬虫夏草 慢性肾衰竭 作用机理 CRF 

分 类 号：R277.51[医药卫生—中医学]