老年原发性骨质疏松患者掌骨皮质指数和骨密度与全身骨量关系的研究  

The Correlation of metacarpal cortical index and bone mineral density with whole body mass in senile primary osteoporosis patients

作　　者：张冬梅[1] Eugene McCloskey John Kanis 

机构地区：[1]上海市东方医院内分泌科,200120 [2]英国谢菲尔德大学代谢性骨病研究中心

出　　处：《中国骨质疏松杂志》2001年第3期213-215,共3页Chinese Journal of Osteoporosis

摘　　要：目的　评价计算机X线密度测量方法的有效性和实用性。方法　对 84例老年原发性骨质疏松患者使用计算机X线密度测量方法测定掌骨皮质指数和骨密度 ,并与双能X线吸收法测定腰椎 ,髋部骨密度和与定量超声技术测量胫骨超声速度进行比较。结果　老年骨质疏松患者掌骨皮质指数和骨密度与腰椎 ,髋部骨密度和胫骨超声骨速度有相关 ,而与年龄和绝经年限呈负相关 ,与BMI无相关关系。结论　计算机X线密度测量方法 ,有价廉 ,非侵入性和广泛易获得的优点 ,是一种新的定量的骨量测定方法 。Objective\ To evaluate the validity of computed X ray densitometry(CXD). Methods\ We measured the bone mineral density on hand radiographs at the midpoint of the second metacarpal on right hand (mBMD) and metacarpal cortical index(MCI)using computed X ray densitometry in 84 senile primary osteoporosis patients.We estimated the correlation of mBMD and MCI with hip and lumbar bone mineral density assessed by DXA and tibial ultrasound velocity (Soundscan2000, Myriad Ultrasound Systems Ltd,Rehovot,Israel). Results\ Both mBMD and MCI positive significantly correlated with hip and lumbar BMD and tibial ultrasound velocity,but negative significantly correlated with age and menopause duration.There is no correlation of mBMD and MCI with BMI. Conclusion\ Computed X ray densitometry (CXD) has potential for the cheap,non invasive and a new quantitative assessment of the bone mass,This technique may be a new alternative method for screening osteoporosis and observation of therapeutic effects.

关 键 词：计算机X线密度测量方法 mBMD MCI 老年原发性骨质疏松 皮质指数 骨密度 

分 类 号：R681[医药卫生—骨科学]