武汉地区1359例骨密度测定及骨质疏松患病率分析  

Measurement of bone mineral density by DEXA and prevalence rate of osteoporosis in 1359 Wuhan residents

作　　者：沈霖[1] 杨艳萍[1] 安锐[1] 汤耿民[2] 赵光[3] 周丕琪[1] 谢晶[1] 高兰[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院,武汉430022 [2]湖北省中医药研究院 [3]铁道部第四勘探设计院医院

出　　处：《中国骨质疏松杂志》2001年第3期232-234,共3页Chinese Journal of Osteoporosis

基　　金：湖北省医药卫生科学研究项目资助(W980 10 )

摘　　要：目的　分析武汉地区人群骨密度 (BMD)变化规律及骨质疏松 (OP)患病率。方法　使用美国Hologic公司双能X线骨密度仪对武汉地区 2～ 91岁的居民 135 9人进行L1～ 4和髋部BMD测定 ,然后进行比较和统计分析。结果　男性腰椎骨峰值在 30～ 34岁年龄段 ,女性在 35～ 39岁 ;男、女性髋部骨峰值均在 30～ 34岁。峰值后随年龄增长BMD逐渐下降 ,女性在 5 0岁后可见明显的骨质丢失加速 ,而男性丢失是逐渐和缓慢的。武汉地区 5 0～ 79岁人群骨质疏松症发病率男性为37 8% ,女性为 6 7 3 %。结论　骨质疏松研究的重点在中老年妇女 ,但对于男性也不能忽视 ;Objective\ To analyse the regularities of change in bone mineral density(BMD) and the prevalence rate of osteoporosis(OP). Methods\ BMD of L 1\|4 and hip was measured by Hologic 2000 plus dual energy X\|ray absorptiometry(DEXA) for 1359 people(615 men,744 women,aged 2 to 91 years).All data of BMD were compared and statistically analyzed. Results\ The BMD peak values of L\-\{1\|4\} could be seen in 30\|34 year old group for males and in 35\|39 year old group for females.However,the peak bone mass of hip was found in 30\|34 year old groups of both sexes.Afterwards BMD diminished with increasing age.The bone loss was sharply decreased for females after 50 years of agte,but that of males was progressive and slow.The prevalence rate of OP in residents aged 50\|79 years old was 37\^8% for men and 67\^3% for women in Wuhan district. Conclusion\ The study of OP is important for females but should not be ignored in males.The preventive measures of OP should be taken among children and young people.

关 键 词：骨密度 骨质疏松症 患病率 武汉 

分 类 号：R681[医药卫生—骨科学]