人甲状旁腺激素结构与功能研究进展  

The advances in study of structure-function relationship of human parathyroid hormone

作　　者：张艳[1] 李成文[2] 赵丹慧[1] 

机构地区：[1]北京积水潭医院骨与关节疾病研究中心,北京100035 [2]军事医学科学院微生物流行病研究所

出　　处：《生物技术通讯》2001年第3期W024-W026,共3页Letters in Biotechnology

摘　　要：甲状旁腺激素 (PTH)分子由 84个氨基酸残基组成。二级结构中富含α 螺旋 ,该螺旋结构在与受体相互作用中起重要作用。探索PTH分子结构与功能间的关系 ,有助于制药工业的发展 ,为临床治疗提供借鉴。The structure of a biological molecule meets the needs of its function. Human parathyroid hormone is composed of 84 amino acid residues. The second structure is α-helix rich. This kind of structure make an important role when the molecule react with its receptors. Studying the structure-function relationship will bring about a great advance in pharmacy production and guide the clinical treatment. The study of structure-function relationship of human parathyroid hormone is reviewed in this essay.

关 键 词：人甲状旁腺激素 结构 功能 研究进展 hPTH 

分 类 号：Q573[生物学—生物化学]