硝酸甘油、前列腺素E_1、心得安对狗急性缺血心肌的影响  

Comparison of Effects of Nitroglycerin, Prostaglandin E_1 and Propranoiol on Acute Ischemic Myocardium

作　　者：许家琍[1,2] 刘伟宏[1,2] 李庚山[1,2] 高荟瑷 王晋明[1,2] 施冰[1,2] 李建军[1,2] 陈芳[1,2] 漆曙辉 唐其柱[1,2] 

机构地区：[1]湖北医学院附属第一医院心内科 [2]湖北医学院血管病研究室

出　　处：《起搏与心脏》1991年第4期203-206,共4页

摘　　要：通过心外膜电图标测、Swan-Ganz导管监测血流动力学及硝基四氮唑染色等方法,比较了硝酸甘油、前列腺素E_1、心得安对急性心肌梗塞范围(IS)和血流动力学的影响。结果表明,三者均能缩小IS,降低各标测点ST段抬高总和和以ST段抬高≥2mV的标测点数,对心输出量、每搏指数、心脏指数、肺毛细血管楔嵌压、心率的影响各不相同,前列腺素E_1既能缩小IS,又有良好的血流动力学效应。The comparison of effects of nitroglycerin, prostaglandin E_1 (PGE_1) and propranolol on infarction size (IS) and hemodynamics during acute myocardial infarction (AMI) were studied by epicardial mapping, N-BT evalution and Swan-Ganz catheterization, etc. The results showed that nitroglycerin, PGE_1 and propranolol all diminish IS, decline ∑ST and NST. However, their effects on CO, SI, CI, PCWP and HR varied differently, POE_1 not only diminished IS but also showed better hemodynamic effects.

关 键 词：硝酸甘油 前列腺素E1 心肌缺血 

分 类 号：R972[医药卫生—药品]