益气活血补肾法对大鼠早期糖尿病肾脏病变的影响  

Effect of Yiqi Huoxue Bushen with Early Diabetic Nephropathy Rats

作　　者：李红[1] 徐蓉娟[1] 唐红[1] 

机构地区：[1]上海中医药大学附属龙华医院内分泌科,上海200032

出　　处：《中国中西医结合肾病杂志》2001年第10期594-596,共3页Chinese Journal of Integrated Traditional and Western Nephrology

基　　金：上海市教委发展基金资助项目 (No .96C13) ;上海市卫生局基金资助项目 [No .泸卫中 ( 1996 ) 2 4-10 3]

摘　　要：目的 :观察益气活血补肾的治糖保肾冲剂治疗早期糖尿病肾病 (DN)的疗效。方法 :采用反复三次腹腔注射链脲佐菌素 (STZ)加福氏完全佐剂 (CFA)造成DN的模型 ,以西药苯那普利为对照 ,观察治糖保肾冲剂治疗早期DN的效果。结果 :治糖保肾冲剂可降低高血糖、甘油三脂 (TG)及尿微量蛋白 ,调节血管活性物质 ,减轻肾脏病理变化。结论 :治糖保肾冲剂通过降糖、降脂、降尿微量蛋白、调节血管活性物质等 。Objective:The observing effect and mechanism of Zhi Tang Bao Shen(ZTBS) soluble preparation which can boost qi,quicken the blood and supplement the Kidney on the early diabetic nephropathy (DN).Methods:Building rat model by Tris-Injecting streptozotocin (STZ) adding fluid complete adjuvant (FCA) into rat enterocoelia repeatedly to result in diabetic nephropathy.ZTBS contrast benazepril.Results:ZTBS can decrease hyperglycemia,triglycerides (TG) and urine micro-Protein.In our practice we found that ZTBS can regulate vasoactive factors and relieve kidney damage in pathology.Conclusion:ZTBS can treat early diabetic nephropathy effectively.

关 键 词：益气活血补肾 治糖保肾冲剂 早期糖尿病肾病 

分 类 号：R259.8[医药卫生—中西医结合]