全蝎提取液对血液凝固的影响  

The Influence of Scorpin Extract Fluid on Blood Coagulation

作　　者：郝晓云[1] 彭延吉[1] 肖长江[1] 

机构地区：[1]湖南中医学院第一附属医院,长沙410007

出　　处：《血栓与止血学》2001年第4期158-159,共2页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的:研究全蝎提取液对血液凝固的影响。方法:采用全蝎提取液给家兔、小鼠静脉注射,并测定其血小板最大聚集率、血栓重量、纤维蛋白原含量及优球蛋白溶解时间的变化。结果:全蝎提取液对血小板最大聚集率有明显抑制作用(P<0.01),使血栓重量明显减轻(P<0.01),纤维蛋白原含量和优球蛋白溶解时间明显减少(P<0.01)。结论:全蝎提取液可通过促进纤溶、抑制血小板聚集而抑制血栓形成。Objective: To study the influence of the scorpin extract fluid(SEF) on blood cogulation. Methods: The changing of platelet aggregation rate, the thrombus weight, the content of fibrinogen and the euglobulin lysis time were determined after SEF iv on rabbit and mice. Results: SEF had the effectiveness of inhibiting platelet aggregation(P<0. 01), decreasing the weight of thrombus(P<0. 01) and decreasing the content of fibrinogon and the eugloblulin lysis time(P<0. 01). Conclusion: SEF inhibits the formulation of the thrombus though the mechanism of improving fibrinogen lysis and inhibiting platelet aggregation.

关 键 词：全蝎提取液 血液凝固 体外血栓 体外血小板 抗血栓作用 

分 类 号：R282.74[医药卫生—中药学] R285[医药卫生—中医学]