感染性疾病患儿SIL-2R和T淋巴细胞亚群的测定  

Detection of soluble interleukin-2 receptor and T lymphocytes subsets in baby and children with infectious diseases

作　　者：营丽娟[1] 何浩明[1] 刘建胜[1] 田小平[1] 

机构地区：[1]江苏省连云港市第一人民医院检验科,222002

出　　处：《淮海医药》2001年第6期447-448,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨了婴幼儿感染性疾病患儿血清 SIL- 2 R和 T淋巴细胞亚群的水平。方法　采用双抗体夹心法测定 SIL - 2 R水平和间接免疫荧光法测定 T淋巴细胞亚群。结果　患者组血清 SIL - 2 R水平显著高于对照组(P<0 .0 1) ,CD3、CD4和 CD4/ CD8比值均降低 (P<0 .0 1) ,CD8水平升高。Objective To explore the serum levels of soluble interleukin 2 receptor(SIL 2R) and T lymphocyte subsets in baby and children with infectious diseases.Methods SIL 2R was dectected with double antobody sandwich ELISA and T lymphocyte subsets with indirect imnunofluorescent technique.Results The patients' SIL 2R level was higher than that in normal controls( P <0.01),CD 8 lymphocyte were increased,while CD 3?CD 4 and the ratio of CD 4 to CD 8 were decreased.Conclusion The cellular imnune function is reduced and the imnune regulation is confused in baby and children with infectious disease.

关 键 词：传染病 白细胞介素2受体 T淋巴细胞亚群 实验室检测 

分 类 号：R446.11[医药卫生—诊断学] R725.1[医药卫生—临床医学]