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作 者:安海滨[1] 荫士安[1] 徐青梅[1] 胡善明[1] 赵显峰[1] 孟晶[1]
机构地区:[1]中国预防医学科学院营养与食品卫生研究所妇幼营养研究室,北京市100050
出 处:《中华预防医学杂志》2001年第6期370-373,共4页Chinese Journal of Preventive Medicine
基 金:"九五"国家科技攻关项目 ( 96 90 4 0 6 0 6 )
摘 要:目的 以孕妇为对象 ,研究孕中期单纯补钙和补钙同时补铁和 /或锌对婴儿生长发育的影响。方法 选择初产健康孕妇 313名 ,分别强化维生素D(VD)、钙、铁和锌 ,从孕 5月至分娩时止。分娩时测量胎盘重量、胎盘和脐带血中微量元素的含量、新生儿的出生体重和身长。结果 对照组胎盘重量最大 ,钙和多种微量元素的含量较低 ,而钙 +铁 +锌 +VD组相反 ,并且对照组的胎盘重量(5 5 1 1± 6 4 2 )g显著大于钙 +铁 +锌 +VD组 (4 6 7 1± 36 6 )g。脐血中血红蛋白含量显著高于母血 ,碱性磷酸酶活性差异无显著性 ,脐血血浆中钙、铁、锌含量均高于母血。婴儿的生长发育结果显示 ,钙 +铁 +锌 +VD组新生儿的出生体重 (3 5 3± 0 33)kg和身长值最大 ,并且出生体重显著大于对照组的 (3 2 8± 0 5 4)kg。结论 孕期联合补充钙、铁、锌 ,使其达到或接近每日膳食中营养素供给量 ,这是改善婴儿生长发育的最佳方式。Objectives The purpose of the present study is to determine the effects of supplementing the biscuits fortified with calcium (Ca), iron (Fe) and zinc (Zn) for pregnant women from the 5th month of gestation until delivery on the growth and development of fetus and to explore the best way to improve infant growth Methods A total of 313 healthy and primary pregnant women were enrolled and divided into five study groups based on their order visiting the hospitals for prenatal care Each woman of the study groups was given three pieces of biscuit fortified with VD, Ca and VD, Ca, Zn and VD (Ca+Zn+VD), Ca, Fe, VC and VD (Ca+Fe+VD), Ca, Fe, VC, Zn and VD (Ca+Fe+Zn+VD), respectively, from the 5th month of gestation until delivery (24 weeks in total) daily The fortified levels were 10 μg VD, 400 mg Ca from carbonate calcium, 10 mg Zn from lactate zinc, 10 mg Fe from ferrous lactate, and 50 mg VC, respectively A parturient women was selected from the same hospital as control after one trial sybject for each study groups selected Placenta was weighed and umbilical cord venous blood and placenta tissue samples were collected after delivery for measureing Ca and other trace elements Body weight and height of the new born babies were measured Results The weight of placenta in control group (551 1±64 2) g was significantly ( P <0 05) heavier than other trial groups with Ca+Fe+Zn+VD (467 1±36 6) g, but contents of Ca and other trace elements in placenta of the control group were lower, which probably because of the lower nutrients intake of mothers in control group that would result in a compensation enlargement of placenta to get enough nutrients for fetus from mother The Hb level in cord venous blood was significantly higher than that of maternal blood There was no significant difference in activity of alkaline phosphatase between cord venous blood and materanl blood The contents of Ca, Fe and Zn in cord venous plasma were all significantly higher than those in maternal plasma Birth weight and
分 类 号:R172[医药卫生—妇幼卫生保健]
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