血栓通注射液质量评价研究  

Comparative study on quality of Xueshuantong injection produced by different manufactures

作　　者：甄健存[1] 陈志刚[1] 常增荣[2] 张小茜[2] 张伟[2] 

机构地区：[1]北京积水潭医院药剂科,北京100035 [2]北京市药品检验所,北京100035

出　　处：《中国药学杂志》2001年第12期847-847,共1页Chinese Pharmaceutical Journal

摘　　要：目的　对国内 3个厂家的血栓通注射液质量进行对比研究 ,为优选药品、控制产品质量提供科学依据。方法　在部颁标准的基础上 ,采用HPLC测定人参皂苷Rg1、Rb1和三七皂苷R1的含量。结果　各厂家的产品质量有较大差异 ,并且各有优势和不足。结论　建议临床优选用药 ,厂家严格管理 。OBJECTIVE: In order to provide the quality control data for the xueshuantong injection products, samples of 3 manufactures were collected and analyzed. METHODS: Based on the quality standard of the ministry, the contents of ginsenosides-Rg1, ginsenosides-Rb1 and saponins-R1 in the injection were determined by RP-HPLC. RESULTS There were some differeces among the samples. CONCLUSION: In order to guarantee the safety and efficacy of the products, it is necessary for manufactures to improve the quality of xuehuantong injection product.

关 键 词：血栓通注射液 高效液相色谱法 质量 

分 类 号：R927.11[医药卫生—药学] R972