救尔心胶囊对大鼠急性心肌缺血的保护作用  

Protecting Effect of Jiuerxin Capsules on Acute M yocardial Ischemia in Rats

作　　者：吴向群 徐鸣 毛靖峰 王栋 

机构地区：[1]江西省药品检验所,330046

出　　处：《中国药师》2001年第4期287-288,共2页China Pharmacist

摘　　要：目的:研究救尔心胶囊(JEXC)对大鼠急性心肌缺血的保护作用。方法:用异丙肾上腺素造成大鼠心肌缺血模型。结 果:JEXC能提高超氧化物歧化酶(SOD)的活性,降低心肌丙二醛(MDA)和血清肌酸酶(CK)含量。结论:JEXC具有抗脂质过 氧化作用,对心肌急性缺血具有保护作用。Objectives: To research the pharmacological actions of Jiuerxin capsules(JEXC)against acute myocardial ischemia in rats. Methods: The rat model of acute myocardial ischmia was established by high-dose isoproterenol subcutaneous injection. Results: Jiu-Er-Xin capsules could increase the activities of SOD and decrease MDA content in myocardium. It also decreased CK content in serum and limited the area of myocardial infarction. Conclusion: Jiuerxin capsules has the action of anti-lipid peroxidation and protecting effect on acute myocardial ischemia.

关 键 词：救尔心胶囊 心肌缺血 保护作用 动物实验 中成药 冠心病 

分 类 号：R259.414[医药卫生—中西医结合] R286.2[医药卫生—中医内科学]