运动疗法对2型糖尿病患者的观察  

The clinical efficacy of exercise training on type 2 diabetes mellitus

作　　者：易鸣[1] 高晓远[1] 张峙[1] 王丽茹[1] 

机构地区：[1]北京复兴医院内科,邮政编码100038

出　　处：《中国糖尿病杂志》2001年第6期357-359,共3页Chinese Journal of Diabetes

摘　　要：目的　 2型糖尿病患者进行有规律的中等强度的运动疗法 ,观察运动前后血糖、胰岛素水平及其曲线下面积、血脂、体重指数 (BMI)、微量尿白蛋白等项的变化。方法　 2 8例患者平均年龄 59.0± 7.6岁 ,在饮食和口服降糖药物治疗的同时 ,每日坚持 1～ 1 .5小时保持中等负荷强度的运动疗法 ,历时 1 2个月 ,观察运动前后上述各项指标的变化 ,并随机与 40例、平均年龄 59.5± 7.3岁 ,以饮食和口服降糖药物治疗为主的 2型糖尿病患者作对照。结果　运动组的血糖及其曲线下面积、Hb Alc、肥胖型患者的 BMI均有明显降低 (P<0 .0 1 ) ,均明显优于对照组 (P<0 .0 1 )。空腹及餐后 2、3小时血浆胰岛素水平亦下降 (P<0 .0 5)。运动疗法对微量尿白蛋白的排出无影响 (P>0 .0 5)。结论　运动疗法能明显降低 2型糖尿病患者的血糖和肥胖者的体重指数 ,改善血脂代谢 ,降低胰岛素抵抗 ,恢复胰岛素的敏感性 ,其作用是单纯药物和饮食疗法不能代替的。Objective To observe the changes of type 2 diabetes mellitus patients in blood sugar,TC,TG,HDL C,plasma insulin,body mass index(BMI), microalbuminuria,etc before and after moderate intensity exercise training.Methods 28 patients with mean age of 59.0±7.6 years did moderate intensity exercise training for 1～1.5 hours every day for 12 month.At the same time they received the treatment of diet and oral antidiabetic drug com pared with 40 controls without exercise training. Before and after the observing period we measured the values of items above.Results Plasma glucose level , HbAlc,AUCGS(the area under the curve of glucose sugar) and BMI in fat diabetes with training team were obviously decreased compared with those before observation( P <0.01) . There were significant difference between two groups in the above( P <0.01). The amount of fasting insulin, 2h insulin and 3h insulin descended in training group( P <0.05). Exercise training had no effect on urinary albumin excretion( P >0.05).Conclusion Exercise training can significantly descend blood sugar, insulin resistance and BMI of obese people ,improve lipidmetabolism and ascend insulin sensitivity. So the action of exercise can't be replaced by the diet and oral drug.

关 键 词：2型糖尿病 运动疗法 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]