流动注射在线过滤稀释原子吸收测定药物制剂中安乃近的方法研究  

Determination of analgin by flow-injection on-line filtration-dilution atomic absorption spectrometry

作　　者：李亚荣[1] 郎惠云[1] 谢志海[1] 焦更生[2] 

机构地区：[1]西北大学化学系,西安710069 [2]渭南师范学院化学系,渭南714000

出　　处：《分析试验室》2001年第6期11-13,共3页Chinese Journal of Analysis Laboratory

摘　　要：提出了测定安乃近的FI AAS分析新方法。此法基于在适当酸度条件下安乃近将Cu2 +还原为Cu+,新生成的Cu+与SCN- 生成沉淀 ,经流动注射在线过滤稀释 ,以AAS法测定反应后剩余Cu2 +的量来间接测定安乃近的含量。安乃近的浓度在 2～ 1 0 0mg/L范围内与吸收值呈良好的线性关系 ,回收率为 97 0 %～ 1 0 2 5 % ,采样频率为 1 0 0次A simple, rapid and selective method for determination of analgin was developed. Analgin could react with Cu 2+ and SCN - to form precipitate quantitatively. The amount of residual Cu 2+ was determined by flow injection on line filtration dilution atomic absorption spectrometry. The content of analgin was then determined indirectly. The linear range is 2～100 μg/mL with recovery of 97 0%～101 7% and sampling frequency of 100 h -1 . The method was applied to determine analgin in samples with satisfactory results.

关 键 词：流动注射 在线过滤 原子吸收法 安乃近 解热镇痛药 药物含量测定 

分 类 号：R971.1[医药卫生—药品] R927.2[医药卫生—药学]