70例新生儿输血及输血制品后巨细胞病毒感染的调查  

Investigation of Newborn Cytomegalovirus Infection after Blood and Blood Product Transfusion: Analysis of 70 cases

作　　者：郑惠童[1] 邹红梅[1] 程冰梅[1] 刘倩筠[1] 高伟玲[1] 黄翠玲[1] 

机构地区：[1]广州市妇婴医院,广东广州510180

出　　处：《中华医院感染学杂志》2001年第6期404-405,共2页Chinese Journal of Nosocomiology

摘　　要：目的　了解婴儿输血和血制品后巨细胞病毒 (CMV)感染情况。方法　 70例产妇分娩前 CMV- Ig G,Ig M均阴性 ,其婴儿因各种疾病需输血及输注其他血制品 ,输注前婴儿血 CMV- Ig M均阴性 ,输注后 3～ 4个月复查CMV- Ig M。结果　 70例婴儿血 CMV- Ig M阳性有 6例 ,发生率为 8.5 7%,输单一种血制品 2 7例 ,CMV - Ig M阳性率是 0 ,输注多种血源的血液及多种血制品 ,CMV- Ig M阳性率是 13.95 %(P<0 .0 5 )。结论　输血和血制品婴儿可以感染 CMV;输多个血源的血液或血制品比输单个血源或血制品感染OBJECTIVE To understand infant cytomegalovirus (CMV) infection after receiving blood transfusion and blood product transfusion. METHODS Seventy lying in women tested CMV IgM, IgM negative before delivery, whose infants received blood tranfusion and blood product transfusion. CMV IgM of the infants were negative before transfusion, which were tested 4 months after transfusion. RESULTS There were six infants with positive CMV IgM in 70 cases (two received albumin and blood exchange transfusion, one received albumin and intravenous γ immunoglobulin, three received albumin, intravenous γ immunoglobulin and whole blood tranfusion). The positive rate was 8.57%. Twenty seven infants received only one blood product, the CMV IgM positive rate was 0. The CMV IgM positive rate of the infants who received blood of multisource and multiple blood products tranfusion was 13.95%, P<0.05. CONCLUSIONS Infants who received blood and blood products transfusion may be infected CMV; Infants who received blood and blood products of multisource transfusion had more chances to be infected CMV.

关 键 词：输血 血制品 CMV 感染 新生儿 

分 类 号：R457[医药卫生—治疗学]