褐藻氨酸降压作用的动物实验研究  

THE EXPERIMENTAL STUDIES OF HYPOTENSIVE ACTIONS OF LAMININE ON ANIMALS

作　　者：安建强[1] 孙世锡[1] 

机构地区：[1]青岛医学院药理学教研室

出　　处：《青岛医学院学报》1991年第2期124-127,共4页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：分别观察了褐藻氨酸对实验动物大鼠、猫和家兔的降压作用。结果表明,静脉注射褐藻氨酸100mg/kg在麻醉大鼠降压29.3±10.2%,在麻醉猫降压21.8±6.8%,在清醒兔降压14.2±14.2%。降压作用在麻醉大鼠呈明显的量效关系,且不产生快速耐受性。The observations of hypotensive actions of laminine on different experimental animals showed that, with 100 mg/kg intravenous injectious, laminine caused the blood pressures of anaesthetized rats, cats and conscious rabbits to decrease 29.3±10.2%, 21.8±6.8%, 14.2±14.2% respectively. A positive correlation was shown between hypotensive effect and dosage of laminine on rats. There was no tachyphylaxis wit repeated sequent intravenous injections of laminine during a short period on rats. h

关 键 词：褐藻氨酸 降压作用 海带 

分 类 号：R931.76[医药卫生—生药学]